These six illustrations were created as a commissioned project for Biosite.
All paintings are © David S. Goodsell 2005.
This illustration shows a portion of basement membrane,
a structure that forms the support between tissues in your body.
It is composed of a network of collagen (yellow green),
laminin (blue-green cross-shaped molecules), and proteoglycans (deep green, with three arms).
Blood serum is shown in the picture, with many Y-shaped antibodies, large circular low density lipoproteins,
and lots of small albumin molecules. The large fibrous structure at lower left is von Willebrand factor and the long molecules in red are fibrinogen, both of which are involved in blood clotting. The
blue object is poliovirus.
A small portion of cytoplasm is shown, including three types of filaments that make up the
cytoskeleton: a microtubule (the largest), an intermediate filament (the knobby one) and two
actin filaments (the smallest ones). The large blue molecules are ribosomes, busy in their
task of synthesizing proteins. The large protein at bottom center is a proteosome.
Part of a muscle sarcomere is shown here, with actin filaments in blue and myosin filaments in red. The long yellow proteins are the huge protein titin.
This view shows DNA being replicated in the nucleus. DNA polymerase is shown at the center in purple, with a DNA strand entering from the bottom and exiting as two strands towards the top. The new strands
are shown in white. Chromatin fibers are shown at either site of the replication fork.
Red Blood Cell
A portion of a red blood cell is shown in this illustration, with the cell membrane at the top,
and lots of hemoglobin (red) at the bottom.